Patient Values and Preferences in Decision Making for Antithrombotic Therapy: A Systematic Review

G panels require the best evidence regarding patient values and preferences in making trade-offs between desirable and undesirable consequences of alternative management strategies. 1 We defi ne “values and preferences” as a broad term that includes patient perspectives, beliefs, expectations, and goals for their health and life, including the process that patients go through in weighing the potential benefi ts, harms, costs, and burdens associated with different treatment or disease management options. 2 Recommendations regarding antithrombotic therapy typically involve trade-offs between decreased risk of thrombosis vs increased bleeding risk and burden of treatment. To inform recommendations of the Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines, we conducted a systematic review to determine what is known regarding patient values and preferences for and experiences with antithrombotic therapy (including prophylaxis and treatment).